DCAR_022381

BLAST of DCAR_022381 vs. ExPASy Swiss-Prot and TrEMBL without DCAR
Match: A0A5B7BLD1 (DNA topoisomerase 2 {ECO:0000256|RuleBase:RU362094} (5.6.2.2 {ECO:0000256|RuleBase:RU362094}) (Fragment))

HSP 1 Score: 2029.22 bits (5256), Expect = 0.000e+0
Identity = 1051/1518 (69.24%), Postives = 1208/1518 (79.58%), Query Frame = 0
 

Query:    5 PLQTNNISNTA------------KSIEETYQKKTQLEHILLRPDTYIGSIEKHTSSLWVYEDSEMVSRSVSYVPGLYKIFDEILVNAADNKQRDPKMDTVKVVIDVDNTLISVYNNGDGVPVEIHKEEGVYVPELIFGHLLTSSNYDDDQKKTTGGRNGYGAKLANIFSTEFVIETADGKRLKKYKQVFSNNMGNKTEPHITKCKESDNWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAGCLGRSVKVELNGERVPIKSFTDYIDLYLKSANKDKEDPLPRFVERVNSRWEICVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNQLTSHIIASISKKNKKVNLKPHAVKNHLWVFVNALIDNPAFDSQTKETLTIRQNSFGSECKLSEDFLKKVVNKSGIVDSLLAWAEFKEKKDLKKTDG-KKGRVTGIPKLEDANKAGGSQSQKCTLILTEGDSAKSLAMAGLSVVGRDLYGVFPLRGKLLNVREASHKQIMENAEIQNIKKILGLQHGKAYEDVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPHFMIEFITPIVKATKNEGAKNEIVLSFYTIPEYENWKESLGDALRGWTIKYYKGLGTSDATEAKAYFRDLGTHKKDFIWAGDDDGDAIELAFSKKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFTKQAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDF--------------------GGKDHASARYIYTELAPITRYMFPKDDDILLDYLYEDGQKIEPYWYVPVVPMVLVNGSEGIGTGWSTYVPNYNPRDIAANIRRLLMGEPMQPMDPWYKGFRGTIEKSATKEAGAGYTVSGLIEEIDDTNVRITELPIRRWTQDYKEFLESSMIGNEKIK-AFIKNYSNQSDDCTVHFDVEMSEENMLIAKQEGLLKKFKLTANISTSNMHLFDPKGVIKKYDSPEQILEDFYHVRFDLYKKRQ---------------------ARVVEGKIKVSNRKKADLFLELKEKGFTPFPKKTK-VEELVAGAT-DAVETEDNSQGSGGAGSAKLGDYDYLLKMEIGTLTAERVQKLLKEKDQLIGEVDELRKATPTSLWLKDLDALDRELDAQDQRDADGEASRVSTYENRMKPDG--SAKKAPKNPRKSTKNVKNAETVVKLTGTATDSAMETEDNVQEVVNPKGKAGPKKAPAKKGKSTSIL---RDEDDDDEILDLKDRLAAYNINSSPDHSEVMEVDVPQKQATKKPPSGKSVAGKK---ASLDVSGDEEQEFEIEDISDDNDSEVEVVKG----KKGGRKPAAGNSKAAAKPPAAPAATKKRGPAATTKKSQLVNQKLITDVLKPAENSGVSPEKKVRKMRASPFNKKSSSVLGRVAAKDDSVSLGSSLDTSGGGGSSETMTRV--------ARPQRVNRTKTTYVLSDSDDNDEEDPTEEEPTDDDDF-EDED 1444
            PLQT+N  N A            K+IEETYQKKTQLEHILLRPDTYIGSIEKHT  LWVYE++EMV RS++YVPGLYKIFDEILVNAADNKQRDP MD+VKVVIDV+   ISVYNNGDGVPVE+H+EEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKL NIFST+FVIETADGKR KKYKQVFSNNMG K+EP ITKCKES+NWTKVSFKPDLAKFNMTHLEDDVVALMKKRV+D+AGCLG++VKVELNG+RVP+KSF DY++LYL+SA+K + D LPR  E+VN RWEICVS SEGQFQQVSFVNGIATIKGGTHVDYVTNQ+T+H+++ ++KKNK  NLK H VKNHLWVFVNALIDNPAFDSQTKETLTIRQ+SFGS+C+LS++FLKKV  KSG+V+SLL+WA+FK+ KDLKKTDG K+ R+TGI KLEDAN AGG  S KCTLILTEGDSAK+LAMAG+SVVGR+ YGVFPLRGKLLNVREASHKQIMENAEIQNIK+ILGLQHGK Y+ VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVP F++EFITPIVKAT     KN  VLSFY++PEYE+WKESLG    GW+IKYYKGLGTS + E K YF+D+G +KKDFIW  + DGDAIELAFSKKKIEARKNWLRQFEPGT+LDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF K+AKVAQFSGYVSEHSAYHHGEQSLA TI+GMAQDF                    GGKDHASARY+YT L+PITR++FPKDDDILLDYL EDGQ IEP WY+PV+P VL+NGSEGIGTGWS+YVPNYNPRDI AN+R LL GEPM+PMDPWYKGFRGTIEK+ATKEAG  YTVSG++EEI++T +RITELPIRRWTQDYKEFLES M GN+KIK  FIK+Y   +DD TVHF+V +SEEN+++AKQEGLLKKFKLT  ISTSNMHLFDP GVIKKY++PEQILE+F+H+R + Y+KR+                       VV+G+I VSNRK+ADLFLEL++KGFTPFPKKTK +E +VAGAT DA E E+NS+        +  DY+YLL M IGTLT E+VQ+L  ++D+L  EVD+LRKATP S+W+ DLDALDRELD Q++ DA  E +R       M   G   +++APKNPRK+ K   NA        +A+ SAMET D++ EVV PKG+AG KKAPA+K +  S++    D+D+DDE+L+LK+RLAAYN+ SSP+HSE ME      +A KK PS ++ A KK      ++S D++ E E+ D   D D ++EVV      KKGGRKPA             PAATKKRGPA   K+SQL+ QKLIT+VLKPAENSG+SPEKKVRKMRASPFNKKSSSVLG     D+   + +  +   G  S               ARPQR NR K  YVLSDS+ +        E TDD  F EDED
Sbjct:   33 PLQTSNNVNVAAAETARSTAGPGKTIEETYQKKTQLEHILLRPDTYIGSIEKHTQPLWVYENNEMVHRSITYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNSISVYNNGDGVPVEVHQEEGVYVPELIFGHLLTSSNYDDTMKKTTGGRNGYGAKLTNIFSTDFVIETADGKRQKKYKQVFSNNMGKKSEPTITKCKESENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVIDLAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSASKTRPDSLPRIAEKVNERWEICVSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMSIVNKKNKNANLKAHTVKNHLWVFVNALIDNPAFDSQTKETLTIRQSSFGSKCELSQEFLKKVA-KSGVVESLLSWADFKQSKDLKKTDGTKRQRITGITKLEDANDAGGKHSDKCTLILTEGDSAKALAMAGISVVGRNYYGVFPLRGKLLNVREASHKQIMENAEIQNIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATH----KNGRVLSFYSMPEYESWKESLGVNASGWSIKYYKGLGTSTSKEGKEYFKDIGKNKKDFIWVDEQDGDAIELAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDFVGSNNINLLQPNGQFGTRHQGGKDHASARYVYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYMPVIPTVLINGSEGIGTGWSSYVPNYNPRDIIANVRCLLSGEPMEPMDPWYKGFRGTIEKTATKEAGVSYTVSGIMEEINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKDPFIKDYREHNDDTTVHFEVILSEENLIMAKQEGLLKKFKLTTTISTSNMHLFDPAGVIKKYETPEQILEEFFHIRLEFYEKRKRVLLDNLELDLLKLENKVRFIIGVVKGEIIVSNRKRADLFLELRDKGFTPFPKKTKTIEAVVAGATDDAEEMEENSE-VVSTKEVRASDYEYLLSMAIGTLTLEKVQELCADRDKLNKEVDDLRKATPKSMWMNDLDALDRELDEQEKSDAQAEVARKEMKSRVMSEAGLKVSRQAPKNPRKNNKKASNA--------SASSSAMET-DDMPEVVKPKGRAGSKKAPARKQEKPSLVLKDEDDDEDDEVLELKERLAAYNLESSPEHSEAMET-----EARKKEPSKRAAAQKKPLSTLTEISDDDDDEVEVGDDIGDEDFDLEVVAAPEEKKKGGRKPA-----------NPPAATKKRGPAK--KQSQLLGQKLITEVLKPAENSGISPEKKVRKMRASPFNKKSSSVLGIRKEDDEEKKISTGSEEKVGSSSPSESVEEMSEVMAPRARPQRANRGKAKYVLSDSESD--------EATDDSSFTEDED 1509    

BLAST of DCAR_022381 vs. ExPASy Swiss-Prot and TrEMBL without DCAR
Match: A0A200R9M6 (DNA topoisomerase 2 {ECO:0000256|RuleBase:RU362094} (5.6.2.2 {ECO:0000256|RuleBase:RU362094}))

HSP 1 Score: 2011.5 bits (5210), Expect = 0.000e+0
Identity = 1034/1525 (67.80%), Postives = 1193/1525 (78.23%), Query Frame = 0
 

Query:    5 PLQTNNISNTA---------KSIEETYQKKTQLEHILLRPDTYIGSIEKHTSSLWVYEDSEMVSRSVSYVPGLYKIFDEILVNAADNKQRDPKMDTVKVVIDVDNTLISVYNNGDGVPVEIHKEEGVYVPELIFGHLLTSSNYDDDQKKTTGGRNGYGAKLANIFSTEFVIETADGKRLKKYKQVFSNNMGNKTEPHITKCKESDNWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAGCLGRSVKVELNGERVPIKSFTDYIDLYLKSANKDKEDPLPRFV---------------------------ERVNSRWEICVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNQLTSHIIASISKKNKKVNLKPHAVKNHLWVFVNALIDNPAFDSQTKETLTIRQNSFGSECKLSEDFLKKVVNKSGIVDSLLAWAEFKEKKDLKKTDG-KKGRVTGIPKLEDANKAGGSQSQKCTLILTEGDSAKSLAMAGLSVVGRDLYGVFPLRGKLLNVREASHKQIMENAEIQNIKKILGLQHGKAYEDVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPHFMIEFITPIVKATKNEGAKNEIVLSFYTIPEYENWKESLGDALRGWTIKYYKGLGTSDATEAKAYFRDLGTHKKDFIWAGDDDGDAIELAFSKKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFTKQAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDF--------------------GGKDHASARYIYTELAPITRYMFPKDDDILLDYLYEDGQKIEPYWYVPVVPMVLVNGSEGIGTGWSTYVPNYNPRDIAANIRRLLMGEPMQPMDPWYKGFRGTIEKSATKEAGAGYTVSGLIEEIDDTNVRITELPIRRWTQDYKEFLESSMIGNEKIK-AFIKNYSNQSDDCTVHFDVEMSEENMLIAKQEGLLKKFKLTANISTSNMHLFDPKGVIKKYDSPEQILEDFYHVRFDLYKKRQ---------------------ARVVEGKIKVSNRKKADLFLELKEKGFTPFPKKTK-VEELVAGAT-DAVETEDNSQGSGGAGSAKLGDYDYLLKMEIGTLTAERVQKLLKEKDQLIGEVDELRKATPTSLWLKDLDALDRELDAQDQRDADGEASRVSTYENRMKPDG--SAKKAPKNPRK-STKNVKNAETVVKLTGTATDSAMETEDNVQEVVNPKGKAGPKKAPAKKGKSTSILRDEDDDDEILDLKDRLAAYNINSSPDHSE-----VMEVDVPQKQATKKPPSGKSVAGKKASL-DVSGDEE--QEFEIEDISDDNDSEVEVV--KGKKGGRKPAAGNSKAAAKPPAAPAAT--KKRGPAATTKKSQLVNQKLITDVLKPAENSGVSPEKKVRKMRASPFNKKSSSVLGRVAAKDDSVSLGSSLDTSGGGGSSETMTRVARPQRVNRTKTTYVLSDSDDNDEEDPTEEE 1433
            PLQT+N  N A         K+IEETYQKKTQLEHILLRPDTY+GSIEKHT +LWVYE  EMV R VSYVPGLYKIFDEILVNAADNKQRDP MD+VKV IDV+   ISVYNNGDGVPVEIH+EEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKL NIFSTEFVI+TADGKR KKYKQVF+NNMG K+EP+ITKCKES+NWTKVSFKPDLAKFNMTHLEDDVVALMKKRV+D+AGCLG++VKVELNG+RVP+KSF DY++LY++SA+K++ D LPRFV                           E+VN RWEICVS SEGQFQQVSFVNGIATIKGGTHVDYVTNQ+T+H++  ++KKNK  NLK H VKNHLWVFVNALIDNPAFDSQTKETLT RQ SFG++C+LS++FLKKV  KSG+V+SLL+WA+FK+ KDLKKTDG K+ R+TGI KLEDAN AGG  S KCTLILTEGDSAK+LAMAG+SVVGR+ YGVFPLRGKLLNVREASHKQIMENAEIQ+IK+ILGLQHGK Y+ VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+P F+IEFITPIVKAT     KN  V+SFY++PEYE WKESLG    GW+IKYYKGLGTS + E K YF+DL  H+KDF+W  + DGDAI+LAFSKKKIEARKNWLRQFEPGT+LDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF K+AKVAQFSGYVSEHSAYHHGEQSLA TI+GMAQD+                    GGKDHASARYIYT L+PITR++FPKDDDILLDYL EDGQ IEP WYVPV+P VLVNGSEGIGTGWS Y+PNYNPRDI  N++RLL GEPM+PMDPWYKGF+G IEK+ATKE G  YTVSG+IEE+++T +RI+ELP+RRWTQDYKEFLES M GN+KIK  FIK+Y   +DD TVHF+V +SEEN+++AKQEGLLKKFKLT  +STSNMHLFDPKGVIKKYD+PEQILE+F+H+R + Y+KR+                       VV+G+I VSNRK+ADLFLEL++KGFTPFPKKTK VE +VAGAT D  E EDNS+     G  +  DY+YLL M IGTLT E+VQ+L  +K +L GEVDELR+AT  SLW KDLDAL++E D QD+ D+  E +R       MK  G   +K   KNPRK +TK V N             S ME E N+ E   PKG+ GP+KAPAKKGK   +  D++DDDEIL+LK+RLAAYN++SSP+ S       ME +    +A  K  S    A KKA++ ++S DE+   + +++ I ++ D E EVV   G+KGG++   G +K AA P AA   T  +KRGP     K QL+NQ LITD+LKPAEN GVSPEKKVRKMRASPFNKKS S+LGRVA +D+  S   S   SG  G  E +   ARPQR NRT   YVLSDS+ +  +D +EEE
Sbjct:    8 PLQTSNNVNVAGSRTQNPPGKTIEETYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYEGGEMVYRPVSYVPGLYKIFDEILVNAADNKQRDPSMDSVKVDIDVEQNCISVYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFTNNMGTKSEPNITKCKESENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVIDMAGCLGKTVKVELNGQRVPVKSFLDYVNLYVQSASKNRPDSLPRFVSDKFESTHSNLFPFRILKQFDFSNRITEKVNDRWEICVSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMTIVNKKNKNANLKAHTVKNHLWVFVNALIDNPAFDSQTKETLTTRQGSFGTKCELSQEFLKKVA-KSGVVESLLSWADFKQSKDLKKTDGAKRQRITGITKLEDANDAGGRNSDKCTLILTEGDSAKALAMAGISVVGRNYYGVFPLRGKLLNVREASHKQIMENAEIQSIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLIEFITPIVKATH----KNGKVMSFYSMPEYEQWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLEKHRKDFMWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYVPVIPTVLVNGSEGIGTGWSCYIPNYNPRDIVENVKRLLNGEPMEPMDPWYKGFKGRIEKTATKEGGVSYTVSGIIEEVNETTLRISELPVRRWTQDYKEFLESIMTGNDKIKEPFIKDYREHNDDTTVHFEVILSEENLVMAKQEGLLKKFKLTTTVSTSNMHLFDPKGVIKKYDNPEQILEEFFHLRLEFYEKRKRVLLENLELELLKLDNKVRFILGVVKGEIIVSNRKRADLFLELQQKGFTPFPKKTKLVEAVVAGATEDTEENEDNSEALSSRG-VRASDYEYLLSMAIGTLTLEKVQELCNDKQRLDGEVDELRRATSKSLWKKDLDALEKEFDEQDKNDSKAEEARKVMKSKVMKEAGMKDSKPVAKNPRKNNTKKVNNPAA--VAASAQVSSTMEIE-NISEAAKPKGRGGPRKAPAKKGKPALVDSDDEDDDEILELKERLAAYNLDSSPEQSSAGPVAAMETESGIVRAKNKETSKMVSAQKKATITEISDDEDNRNDEQMKTIMENEDFEPEVVVPAGRKGGKR---GQTKPAANPKAAKPVTVARKRGPT----KKQLLNQTLITDILKPAENVGVSPEKKVRKMRASPFNKKSGSLLGRVAKEDEEESPMGSEQQSGSSG--EVVATRARPQRANRTVAKYVLSDSEPDAADDFSEEE 1514    

BLAST of DCAR_022381 vs. ExPASy Swiss-Prot and TrEMBL without DCAR
Match: A0A2R6RA79 (DNA topoisomerase 2 {ECO:0000256|RuleBase:RU362094} (5.6.2.2 {ECO:0000256|RuleBase:RU362094}))

HSP 1 Score: 2009.19 bits (5204), Expect = 0.000e+0
Identity = 1019/1472 (69.23%), Postives = 1180/1472 (80.16%), Query Frame = 0
 

Query:    5 PLQTNNISNTAKSIEETYQKKTQLEHILLRPDTYIGSIEKHTSSLWVYEDSEMVSRSVSYVPGLYKIFDEILVNAADNKQRDPKMDTVKVVIDVDNTLISVYNNGDGVPVEIHKEEGVYVPELIFGHLLTSSNYDDDQKKTTGGRNGYGAKLANIFSTEFVIETADGKRLKKYKQVFSNNMGNKTEPHITKCKESDNWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAGCLGRSVKVELNGERVPIKSFTDYIDLYLKSANKDKEDPLPRFVERVNSRWEICVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNQLTSHIIASISKKNKKVNLKPHAVKNHLWVFVNALIDNPAFDSQTKETLTIRQNSFGSECKLSEDFLKKVVNKSGIVDSLLAWAEFKEKKDLKKTDG-KKGRVTGIPKLEDANKAGGSQSQKCTLILTEGDSAKSLAMAGLSVVGRDLYGVFPLRGKLLNVREASHKQIMENAEIQNIKKILGLQHGKAYEDVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPHFMIEFITPIVKATKNEGAKNEIVLSFYTIPEYENWKESLGDALRGWTIKYYKGLGTSDATEAKAYFRDLGTHKKDFIWAGDDDGDAIELAFSKKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFTKQAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDF--------------------GGKDHASARYIYTELAPITRYMFPKDDDILLDYLYEDGQKIEPYWYVPVVPMVLVNGSEGIGTGWSTYVPNYNPRDIAANIRRLLMGEPMQPMDPWYKGFRGTIEKSATKEAGAGYTVSGLIEEIDDTNVRITELPIRRWTQDYKEFLESSMIGNEKIK-AFIKNYSNQSDDCTVHFDVEMSEENMLIAKQEGLLKKFKLTANISTSNMHLFDPKGVIKKYDSPEQILEDFYHVRFDLYKKRQA---------------------RVVEGKIKVSNRKKADLFLELKEKGFTPFPKKTK-VEELVAGATDAVETEDNSQGSGGAGSAKLGDYDYLLKMEIGTLTAERVQKLLKEKDQLIGEVDELRKATPTSLWLKDLDALDRELDAQDQRDADGEASRVSTYENRMKPDG--SAKKAPKNPRKSTKNVKNAETVVKLTGTATDSAMETEDNVQEVVNPKGKAG-PKKAPAKKGKSTSILR-DEDDDDEILDLKDRLAAYNIN-SSPDHSEVMEVDVPQKQATKKPPSGKSVAGKKASLDVS----GDEEQEFEIEDISDDNDSEVEVVKGKKGGRKPAAGNSKAAAKPPAAPAATKKRGPAATTKKSQLVNQKLITDVLKPAENSGVSPEKKVRKMRASPFNKKSSSVLGRVAAKDDSVS-------LGSSLDTSGGGGSSETMTRVARPQRVNRTKTTY 1416
            PLQT+N  N  K+IEETYQKKTQLEHILLRPDTYIGSIE H  +LWVYE+SEMV RSVS VPGLYKIFDEILVNAADNKQRDP MD +KV IDV+   I+VYNNGDGVPVEIH+EEGVYVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKL NIFSTEFVIETADGKR KKYKQVFSNNMG K+EP ITKCKE +NWTKVSF+PDLAKFNMTHLEDDVVALMKKRV+DIAGCLG++VKVELNG+RVP+KSF DY++LYL+SA+K + DPLPR  E+VN RWEICVS SEGQFQQVSFVNGIATIKGGTHVDY+TNQ+T++++  ++KKNK  N+K H VKNHLWVFVNALIDNPAFDSQTKETLTIR +SFGS+C+LS++FLKK V+KSG+V+SLL+WA+FK+ KDLKKTDG K+ R+TGI KLEDAN AGG  S KCTLILTEGDSAK+LAMAG+SVVGR+ YGVFPLRGKLLNVREA+HKQIMENAEIQNIK+ILGLQHGK Y+ VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVP F++EFITPIVKAT     KN  VLSFY++PEYE+WKESLG    GW+IKYYKGLGTS + E K YF DL  HKKDFIW  + DG+AIELAFSKKKIEARKNWLRQ EPGT+LDQ+EKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF K+AKVAQFSGYVSEHSAYHHGEQSLASTI+GMAQD+                    GGKDHASARYIYT L+PITR++FPKDDDILLDYL EDGQ IEP WY+P++P VLVNGSEGIGTGWS+Y+PNYNPRD+ AN++ LL GEPM+PMDPWYKGFRG IEK+ATKE G  YTV+G+IEE+++T +RITELPIRRWT DYKEFLES M GN+KIK  FIK+Y   +DD TVHF+V +SEEN+++AKQEGLLKKFKLT  ISTSNMHLFD  GVIKKYD+PE+ILE+F+H R   Y+KR+A                      VV+G+I VSNRK+ADLFLEL++KGFTPFPKKTK VE  V GATD VE  + S     +   +  DY+YLL M IGTLT E+VQ+L  E+D+L  EVD+LRKATP SLW+ DLDAL++ L  QD+ DA  E +R       M   G   +++ PKNPRK++K   NAE+V + T  +T S+MET DNV EVV PKG  G PKKAPA+K K + +L+ D+DDDDE+L+LK+RLAAYN++ SSPD S  ME +VP   A KK P+ ++   KK    V+     D+E++   ED   + ++  EV K K+ GRKP+A N+K AAKP   PA TKKR PA   K+S    QKLIT++LKP EN G+SPEKKVRKMRASPFNKKS SVLGR+  + +  +       LGS+        +SE M   ARP R+NR K  Y
Sbjct:    8 PLQTSNNVNVPKTIEETYQKKTQLEHILLRPDTYIGSIEHHAQALWVYENSEMVHRSVSVVPGLYKIFDEILVNAADNKQRDPSMDAMKVSIDVEGNCITVYNNGDGVPVEIHQEEGVYVPEMIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSNNMGKKSEPIITKCKEGENWTKVSFRPDLAKFNMTHLEDDVVALMKKRVIDIAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSASKARPDPLPRITEKVNERWEICVSISEGQFQQVSFVNGIATIKGGTHVDYITNQITNYVMGIVNKKNKNANVKAHTVKNHLWVFVNALIDNPAFDSQTKETLTIRPSSFGSKCELSQEFLKK-VSKSGVVESLLSWADFKQSKDLKKTDGTKRQRITGITKLEDANDAGGKNSDKCTLILTEGDSAKALAMAGISVVGRNYYGVFPLRGKLLNVREANHKQIMENAEIQNIKQILGLQHGKQYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATH----KNGKVLSFYSMPEYESWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFNDLSKHKKDFIWVDEQDGEAIELAFSKKKIEARKNWLRQLEPGTYLDQREKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQTIEPIWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDVVANVKHLLNGEPMEPMDPWYKGFRGAIEKTATKETGVSYTVTGIIEEVNETTLRITELPIRRWTLDYKEFLESIMTGNDKIKDPFIKDYREHNDDTTVHFEVILSEENLIMAKQEGLLKKFKLTTTISTSNMHLFDQNGVIKKYDTPEEILEEFFHARLGFYEKRKAILLDNLELDLLKLENKVRFILGVVKGEIIVSNRKRADLFLELRDKGFTPFPKKTKIVEAAVVGATDDVEETEESPDVIASKGIRASDYEYLLSMAIGTLTLEKVQELCAERDKLNKEVDDLRKATPKSLWINDLDALEKVLGEQDESDAQAEDARKKMKSRVMTEAGLKVSRQPPKNPRKNSKKATNAESVSESTALSTSSSMET-DNVAEVVKPKGGRGAPKKAPARKEKPSMVLKDDDDDDDEVLELKERLAAYNLDESSPDQSGAMETEVPPVPAGKKEPNRRAAGQKKPLSTVTEISDSDDEKDASDEDFELEEEAVPEVGKTKR-GRKPSA-NTKVAAKP---PAPTKKRVPA--NKQS----QKLITEILKPVENMGISPEKKVRKMRASPFNKKSGSVLGRMGKEGEENTSTGSEERLGSASTAESTEDTSEVMVPRARPPRMNRGKVRY 1462    

BLAST of DCAR_022381 vs. ExPASy Swiss-Prot and TrEMBL without DCAR
Match: A0A2R6QKP4 (DNA topoisomerase 2 {ECO:0000256|RuleBase:RU362094} (5.6.2.2 {ECO:0000256|RuleBase:RU362094}))

HSP 1 Score: 2007.65 bits (5200), Expect = 0.000e+0
Identity = 1030/1498 (68.76%), Postives = 1204/1498 (80.37%), Query Frame = 0
 

Query:    5 PLQTNNISNTAKSIEETYQKKTQLEHILLRPDTYIGSIEKHTSSLWVYEDSEMVSRSVSYVPGLYKIFDEILVNAADNKQRDPKMDTVKVVIDVDNTLISVYNNGDGVPVEIHKEEGVYVPELIFGHLLTSSNYDDDQKKTTGGRNGYGAKLANIFSTEFVIETADGKRLKKYKQVFSNNMGNKTEPHITKCKESDNWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAGCLGRSVKVELNGERVPIKSFTDYIDLYLKSANKDKEDPLPRFVERVNSRWEICVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNQLTSHIIASISKKNKKVNLKPHAVKNHLWVFVNALIDNPAFDSQTKETLTIRQNSFGSECKLSEDFLKKVVNKSGIVDSLLAWAEFKEKKDLKKTDG-KKGRVTGIPKLEDANKAGGSQSQKCTLILTEGDSAKSLAMAGLSVVGRDLYGVFPLRGKLLNVREASHKQIMENAEIQNIKKILGLQHGKAYEDVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPHFMIEFITPIVKATKNEGAKNEIVLSFYTIPEYENWKESLGDALRGWTIKYYKGLGTSDATEAKAYFRDLGTHKKDFIWAGDDDGDAIELAFSKKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFTKQAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDF--------------------GGKDHASARYIYTELAPITRYMFPKDDDILLDYLYEDGQKIEPYWYVPVVPMVLVNGSEGIGTGWSTYVPNYNPRDIAANIRRLLMGEPMQPMDPWYKGFRGTIEKSATKEAGAGYTVSGLIEEIDDTNVRITELPIRRWTQDYKEFLESSMIGNEKIK-AFIKNYSNQSDDCTVHFDVEMSEENMLIAKQEGLLKKFKLTANISTSNMHLFDPKGVIKKYDSPEQILEDFYHVRFDLYKKRQA---------------------RVVEGKIKVSNRKKADLFLELKEKGFTPFPKKTK-VEELVAGATDAVETEDNSQGSGGAGSAKLGDYDYLLKMEIGTLTAERVQKLLKEKDQLIGEVDELRKATPTSLWLKDLDALDRELDAQDQRDADGEASRVSTYENRMKPDG--SAKKAPKNPRKSTKNVKNAETVVKLTGTATDSAMETEDNVQEVVNPKGKAGPKKAPAKKGKSTSILRDEDDDDEILDLKDRLAAYNINSSPDHSEVMEVDVPQKQATKKPPSGKSVAGKKASLDV---------SGDEEQEFEIEDISDDNDSEVEVVKGKKGGRKPAAGNSKAAAKPPAAPAATKKRGPAATTKKSQLVNQKLITDVLKPAENSGVSPEKKVRKMRASPFNKKSSSVLGRVAAK-DDSVSLGS--SLDTSGGGGSSETMTRV----ARPQRVNRTKTTYVLSDSDDN---DEEDPTEEEPTDD 1437
            PLQT+N +N  K+IEETYQKKTQLEHILLRPDTYIGSIE HT +LWVYE+SEMV RSVS+VPGLYKIFDEILVNAADNKQRDP MD +KV IDV+   I+VYNNGDGVPVEIH+EEGVYVPE+IFGHLLTSSNYDD +KKTTGGRNGYGAKL NIFSTEFVIETADG+R KKYKQ+FSNNMG K+EP ITKCKE +NWTKVSFKPDLAKFNMTHLEDDVVALMKKRV+DIAGCLG++VKVELNG+R P+KSF DY+ LYL+SA+K + DPLPR  E+VN RWEICVS SEGQFQQVSFVNGIATIKGGTHVDY+TNQ+T++++  ++KKNK  N+K H VKNHLWVFVNALIDNPAFDSQTKETLTIR +SFGS+C+LS++FLKK V+KSG+V+SLL+WA+FK+ KDLKKTDG K+ R+TGI KLEDAN AGG  S KCTLILTEGDSAK+LAMAG+SVVGR+ YGVFPLRGKLLNVREASHKQIMENAEIQN+K+ILGLQHGK Y+ VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVP F++EFITPIVKAT     KN  VLSFY++PEYE+WKESLG    GW+IKYYKGLGTS + E K YF DL  HKKDFIW  + DG+AIELAFSKKKIEARKNWLRQ EPGT+LDQ+EKLI+YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF K+AKVAQFSGYVSEHSAYHHGEQSLASTI+GMAQD+                    GGKDHASARYIYT+L+P+TR++FPKDDDILLDYL EDGQ IEP WY+P++PMVLVNGSEGIGTGWS+Y+PNYNPR+I AN++RLL GEPM+PMDPWYKGFRGTIEK+ATKE G  YTV+G+IEE+++T +RITELPIRRWT DYKEFLES M GN+KIK  FIK+Y   +DD TVHF+V +SEEN+++AKQEGLLKKFKLT  ISTSNMHLFD   VIKKYD+PE+ILE+F+H R + Y+KR+A                      VV+G+I VSNRK+ DLFLEL++K FTPFPKKTK VE  V GA D  E  + S     +   +  DY+YLL M IGTLT E+VQ+L  E+D+L  EVD+LRKATP SLW+ DLDAL+R L  QD+ DA  E +R       M   G   +++ PKNPRK++K   NAE+V +    +T S+MET DNV EVV PKG+A PKKA A+K K + +L+D+DDDDE+L LK+RLAAYN+ SSPDHS  ME++VP+  A KK PSG++ A KK    V             E +FE+E+     ++  EV K KK GRKP+A N+K AAKP   PA TKKR PAA  K+SQ+ +QKLIT++L+P EN G+ PEKKVRKMRASPFNKKS+SVLG +  +  +S S GS   L ++    S+E M+ V    ARP R+NR K  YV+SDS+ +   D+ D  E E +DD
Sbjct:    7 PLQTSNNANVPKTIEETYQKKTQLEHILLRPDTYIGSIEHHTQALWVYENSEMVHRSVSFVPGLYKIFDEILVNAADNKQRDPSMDVMKVSIDVEGNCITVYNNGDGVPVEIHQEEGVYVPEMIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRQKKYKQIFSNNMGKKSEPIITKCKEGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVIDIAGCLGKTVKVELNGQRAPVKSFLDYVSLYLQSASKARPDPLPRITEKVNERWEICVSISEGQFQQVSFVNGIATIKGGTHVDYITNQITNYVMGIVNKKNKNANVKSHTVKNHLWVFVNALIDNPAFDSQTKETLTIRPSSFGSKCELSQEFLKK-VSKSGVVESLLSWADFKQSKDLKKTDGTKRQRITGITKLEDANDAGGKNSDKCTLILTEGDSAKALAMAGISVVGRNYYGVFPLRGKLLNVREASHKQIMENAEIQNVKQILGLQHGKQYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATH----KNGKVLSFYSMPEYESWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFNDLVKHKKDFIWVDEQDGEAIELAFSKKKIEARKNWLRQLEPGTYLDQREKLIRYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTQLSPVTRFLFPKDDDILLDYLNEDGQSIEPIWYMPIIPMVLVNGSEGIGTGWSSYIPNYNPREIVANVKRLLNGEPMEPMDPWYKGFRGTIEKTATKETGVSYTVTGIIEEVNETTLRITELPIRRWTLDYKEFLESIMTGNDKIKDPFIKDYREHNDDTTVHFEVILSEENLILAKQEGLLKKFKLTTTISTSNMHLFDQNCVIKKYDTPEEILEEFFHARLEFYEKRKAILLDNLELDLLKLENKVRFILGVVKGEIIVSNRKRVDLFLELRDKDFTPFPKKTKIVEAAVVGAIDDAEETEESPDIIASKGVRASDYEYLLSMAIGTLTLEKVQELCAERDKLNKEVDDLRKATPKSLWMNDLDALERVLGEQDESDAQAEDARKKMKNRVMTEAGLKVSRQPPKNPRKNSKKATNAESVSESMAASTSSSMET-DNVTEVVKPKGRAAPKKAAARKEKLSMVLKDDDDDDEVLQLKERLAAYNLESSPDHSGAMEIEVPRVPAGKKEPSGRAAAQKKPLSAVTEISDDEDDEDTSEDDFELEE-----EAIPEVGKTKK-GRKPSA-NTKVAAKP---PAPTKKRAPAA-NKQSQIKDQKLITEILQPVENMGILPEKKVRKMRASPFNKKSASVLGWIVKEGKESTSTGSDKKLGSASTAESTEDMSEVMAPRARPPRMNRGKARYVVSDSESDKVSDDSDFDESELSDD 1487    

BLAST of DCAR_022381 vs. ExPASy Swiss-Prot and TrEMBL without DCAR
Match: A0A835DDD2 ((Uncharacterized protein {ECO:0000313|EMBL:KAF8396139.1}))

HSP 1 Score: 2006.11 bits (5196), Expect = 0.000e+0
Identity = 1025/1524 (67.26%), Postives = 1190/1524 (78.08%), Query Frame = 0
 

Query:    5 PLQTNNISNTA---------KSIEETYQKKTQLEHILLRPDTYIGSIEKHTSSLWVYEDSEMVSRSVSYVPGLYKIFDEILVNAADNKQRDPKMDTVKVVIDVDNTLISVYNNGDGVPVEIHKEEGVYVPELIFGHLLTSSNYDDDQKKTTGGRNGYGAKLANIFSTEFVIETADGKRLKKYKQV------------------------FSNNMGNKTEPHITKCKESDNWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAGCLGRSVKVELNGERVPIKSFTDYIDLYLKSANKDKEDPLPRFVERVNSRWEICVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNQLTSHIIASISKKNKKVNLKPHAVKNHLWVFVNALIDNPAFDSQTKETLTIRQNSFGSECKLSEDFLKKVVNKSGIVDSLLAWAEFKEKKDLKKTDG-KKGRVTGIPKLEDANKAGGSQSQKCTLILTEGDSAKSLAMAGLSVVGRDLYGVFPLRGKLLNVREASHKQIMENAEIQNIKKILGLQHGKAYEDVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPHFMIEFITPIVKATKNEGAKNEIVLSFYTIPEYENWKESLGDALRGWTIKYYKGLGTSDATEAKAYFRDLGTHKKDFIWAGDDDGDAIELAFSKKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFTKQAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDF--------------------GGKDHASARYIYTELAPITRYMFPKDDDILLDYLYEDGQKIEPYWYVPVVPMVLVNGSEGIGTGWSTYVPNYNPRDIAANIRRLLMGEPMQPMDPWYKGFRGTIEKSATKEAGAGYTVSGLIEEIDDTNVRITELPIRRWTQDYKEFLESSMIGNEKIK-AFIKNYSNQSDDCTVHFDVEMSEENMLIAKQEGLLKKFKLTANISTSNMHLFDPKGVIKKYDSPEQILEDFYHVRFDLYKKRQ---------------------ARVVEGKIKVSNRKKADLFLELKEKGFTPFPKKTK-VEELVAGATDAVETEDNSQGSGGAGSAKLGDYDYLLKMEIGTLTAERVQKLLKEKDQLIGEVDELRKATPTSLWLKDLDALDRELDAQDQRDADGEASRVSTYENRMKPDGS--AKKAPKNPRKSTKNVKNAETVVKLTGTATDSAMETEDNVQEVVNPKGK-AGPKKAPAKKGKSTSILRDEDDDDEILDLKDRLAAYNINSSPDHSEVMEVDVPQKQATKKPPSGKSVAGKKASLDVSGDEEQEFEIEDISDDNDSEVEVVKGKKGGRKPAAGNSKAAAKPPAAPAATKKRGPAATTKKSQLVNQKLITDVLKPAENSGVSPEKKVRKMRASPFNKKSSSVLGRVAAKDD--SVSLGS----SLDTSGGGGSSETMTRVARPQRVNRTKTTYVLSDSDDNDEEDPTEEEPTDDDDFED 1442
            PLQT+N +N A         K+IEETYQKKTQLEHILLRPDTYIGSIEKHT +LW++E  EMV R V+YVPGLYKIFDEILVNAADNKQRD  MD+VKV IDV+   ISVYNNGDGVPVEIH+EEGVYVPE+IFGHLLTSSNY+D +KKTTGGRNGYGAKL NIFSTEFVI+TADGKR KKYKQV                        F NNMG K+EP ITKCKES+NWTKVSFKPDLAKFNMTHLEDDVVALMKKRV+D+AGCLG++VKVELNG+RVP+KSF DY++LYL+SANK + + LPR  E+VN RWEICVS SEGQFQQVSFVN IATIKGGTHVDYVTNQ+T+H+++ ++KKNK  N+K H VKNHLWVFVNALIDNPAFDSQTKETLTIRQ+SFGS+C+LS++FLKKV  KSG+V++LL+WA+FK+ KDLKKTDG K+ R+TGI KLEDAN AGG  S KCTLILTEGDSAK+LAMAG+SVVGR+ YGVFPLRGKLLNVREA+HKQIM+NAEIQNIK+ILGLQHGK Y+ VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSL+KVP F++EFITPIVKAT     KN  V +FY++PEYE+WKESLG    GW+IKYYKGLGTS + E K YFRDL  HKKDF+W  + DGDAIELAFSKKKIEARKNWLRQFEPGT+LDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF K+AKVAQFSGYVSEHSAYHHGEQSLASTI+GMAQD+                    GGKDHASARYIYT L+PITR +FPKDDDILLDYL EDGQ IEP WYVP++P VLVNGSEGIGTGWS+Y+PNYNPRDI AN+R L+ GEPM+PMDPWYKGF+GTIEK+ATKEAG  YTVSG+IEEI++T +RITELP+RRWTQDYKEFLE++M GN+KIK  FIK+Y   +DD TV+FDV +SEEN+++AKQEGL+KKFKLT  +STSNMHLFDPKG+IKKYD+PEQILE+F+H+R  +Y+KR+                       VV+G+I V+NRK+ADLFLEL+ KGFTPFPKKTK V+ +VAGAT+  E  +  +    +   +  DY+YLL M IGTLT E+VQ+L   KD+L  EVDELRKATP SLW++DL+AL++ELD QD+ DA+ E +R       +   GS  +++APKNPRK   N  N E   +    +  S ME   NV EVV PKG+ AGP+KAPAKK K+  +  DE DD+E+L+LKDRLAAYN+ SSPDH E ME + PQ  A KK PS K               E+ +E    +DDND + E   GKKGGRKP A N+K A KP   P A +KRG     ++  ++ QKLIT+VLKPAEN+GVSPEKKVRKMRASPFNKKS S+LGRV  +DD  S   GS       +      SE M   ARPQR NR +T YVLSD++         +E  DD DF D
Sbjct:    8 PLQTSNNANVASSRAAAPPGKTIEETYQKKTQLEHILLRPDTYIGSIEKHTQTLWIFEGGEMVHRPVTYVPGLYKIFDEILVNAADNKQRDQSMDSVKVDIDVEQNCISVYNNGDGVPVEIHQEEGVYVPEMIFGHLLTSSNYNDAEKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVQSFRIEVYGYVLYNSVISSSVMKVFLNNMGKKSEPTITKCKESENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVIDLAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSANKSRPESLPRIAEKVNDRWEICVSLSEGQFQQVSFVNSIATIKGGTHVDYVTNQITNHVMSIVNKKNKNANVKAHTVKNHLWVFVNALIDNPAFDSQTKETLTIRQSSFGSKCELSQEFLKKVA-KSGVVENLLSWADFKQSKDLKKTDGAKRQRITGITKLEDANDAGGRNSDKCTLILTEGDSAKALAMAGISVVGRNYYGVFPLRGKLLNVREANHKQIMDNAEIQNIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLMKVPSFLVEFITPIVKATN----KNGRVFAFYSMPEYESWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFRDLEKHKKDFVWVDEKDGDAIELAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPITRSLFPKDDDILLDYLNEDGQTIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRHLMNGEPMEPMDPWYKGFKGTIEKAATKEAGVSYTVSGIIEEINETTLRITELPVRRWTQDYKEFLETNMTGNDKIKDPFIKDYREHNDDTTVYFDVILSEENLMMAKQEGLMKKFKLTTTLSTSNMHLFDPKGIIKKYDTPEQILEEFFHLRLVVYEKRKKVLLENLELELLKLDNKVRFILGVVKGEIIVNNRKRADLFLELQRKGFTPFPKKTKTVDAVVAGATEDTEENEEKEEVVNSRGVRASDYEYLLSMAIGTLTLEKVQELCANKDRLNNEVDELRKATPKSLWMEDLNALEKELDEQDKNDANAEEARKQIKGRVISGAGSKVSRQAPKNPRKKAAN--NPEPAAESVAASVSSEMEL-GNVPEVVKPKGRAAGPRKAPAKKEKTILVDSDE-DDEEVLELKDRLAAYNLESSPDHLEAMETEEPQVPAGKKEPSRK---------------EKIWE----NDDNDEDFEPQVGKKGGRKPTA-NAK-AGKP---PTAARKRG-QGNKQQPPVLTQKLITEVLKPAENAGVSPEKKVRKMRASPFNKKSGSLLGRVVKEDDEESSPTGSEEKSGSASGSSEEVSEVMVARARPQRANRGQTRYVLSDTES--------DEAADDSDFSD 1489    

BLAST of DCAR_022381 vs. ExPASy Swiss-Prot and TrEMBL without DCAR
Match: A0A068UHP8 (DNA topoisomerase 2 {ECO:0000256|RuleBase:RU362094} (5.6.2.2 {ECO:0000256|RuleBase:RU362094}))

HSP 1 Score: 2001.1 bits (5183), Expect = 0.000e+0
Identity = 1024/1486 (68.91%), Postives = 1203/1486 (80.96%), Query Frame = 0
 

Query:    2 ANRPLQTNNISN----TAKSIEETYQKKTQLEHILLRPDTYIGSIEKHTSSLWVYEDSEMVSRSVSYVPGLYKIFDEILVNAADNKQRDPKMDTVKVVIDVDNTLISVYNNGDGVPVEIHKEEGVYVPELIFGHLLTSSNYDDDQKKTTGGRNGYGAKLANIFSTEFVIETADGKRLKKYKQVFSNNMGNKTEPHITKCKESDNWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAGCLGRSVKVELNGERVPIKSFTDYIDLYLKSANKDKEDPLPRFVERVNSRWEICVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNQLTSHIIASISKKNKKVNLKPHAVKNHLWVFVNALIDNPAFDSQTKETLTIRQNSFGSECKLSEDFLKKVVNKSGIVDSLLAWAEFKEKKDLKKTDG-KKGRVTGIPKLEDANKAGGSQSQKCTLILTEGDSAKSLAMAGLSVVGRDLYGVFPLRGKLLNVREASHKQIMENAEIQNIKKILGLQHGKAYEDVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPHFMIEFITPIVKATKNEGAKNEIVLSFYTIPEYENWKESLGDALRGWTIKYYKGLGTSDATEAKAYFRDLGTHKKDFIWAGDDDGDAIELAFSKKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFTKQAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDF--------------------GGKDHASARYIYTELAPITRYMFPKDDDILLDYLYEDGQKIEPYWYVPVVPMVLVNGSEGIGTGWSTYVPNYNPRDIAANIRRLLMGEPMQPMDPWYKGFRGTIEKSATKEAGAGYTVSGLIEEIDDTNVRITELPIRRWTQDYKEFLESSMIGNEKIK-AFIKNYSNQSDDCTVHFDVEMSEENMLIAKQEGLLKKFKLTANISTSNMHLFDPKGVIKKYDSPEQILEDFYHVRFDLYKKRQ---------------------ARVVEGKIKVSNRKKADLFLELKEKGFTPFPKKTKVEELVAGAT-DAVETEDNSQGSGGAGSAKLGDYDYLLKMEIGTLTAERVQKLLKEKDQLIGEVDELRKATPTSLWLKDLDALDRELDAQDQRDADGEASRVSTYENRMKPDG--SAKKAPKNPRKSTKNVKNAETVVKLTGTATDSAMETEDNVQEVVNPKGKAGPKKAPAKKGKSTSILR--DEDDDDEILDLKDRLAAYNI-NSSPDHSEVMEVDVPQKQATKKPPSGKSVAGKKASLDVSGDEEQEFEIEDISDDNDSEVEV-VKGKKGGRKPAAGNSKAAAKPPAAPAATKKRGPAATTKKSQLVNQKLITDVLKPAENSGVSPEKKVRKMRASPFNKKSSSVLGRVAAKD-----DSVSLGSSLDTSGGGGSSETMTRV----ARPQR-VNRTKTTYVLSDSDD 1423
            A  PLQ++N +N    T K+IEETYQKK+QLEHILLRPDTYIGSIEKH+ +LWV+E+  MV R +SYVPGLYKIFDEILVNAADNKQRDP+MD+VK+VI+V+   ISVYNNGDGVPVE+H+EEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKL NIFSTEFVIE+ADG+R KKYKQVFSNNMGNK++P I+KCKES+NWTKV++KPDLAKFNMTHLEDDVVALMKKRVVD+AGCLG++VKVELNG+RVP+KSF+DY DLYL+SA K + DPLPR VE+VN RWE+C S SEGQFQQVSFVNGIATIKGGTHVDYVTNQ+T+HII  ++KKNK  NLK H+VKNHLWVFVNALIDNPAFDSQTKETLT+RQ+SFGS+C+LS++FLKKV  KSG+V++LL+WA+FK+ KDLKKTDG K+ R+TGI KLEDAN AGG  S +CTLILTEGDSAK+LAMAG+SVVGR+ YGVFPLRGKLLNVREASHKQIM+NAEIQ IK+ILGLQHGK Y+ VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+P F++EFITPIVKAT     KN  VLSFYT+PEYE+WKESL     GW+IKYYKGLGTS + E K YF+DLG HKKDFIW  D+DG+AIELAFSKKKIEARKNWLRQFEPGT+LDQKEKLIKYSDF+NKELILFS+ADLQRSIPSMVDGLKPGQRKILFCSFKRNF K+AKVAQFSGYVSEHSAYHHGEQSLAS I+GMAQDF                    GGKDHASARY+YT L+PITR +FPKDDDILLDYL EDGQ IEP WY+P++PMVLVNGSEGIGTGWS+Y+PNYNPRDI  NIRRLL  EPM+PM+PWYKGFRGTIEK+ATKEAGA YTVSG++EE+D+T +R+TELP+R+WTQDYKEFLES M+GNEK+K  FIK + + +DD TV+ D+ MSEEN+L+AKQEGLLKKFKLT  ISTSNMHLFD +G+IKK+D+PEQILE+F+H+R + Y+KR+                       VVEG I VSNRK+ADLFLELKEKGFTPFPKK  VE  VAG+  DA ETE++S+ +   G  +  DY+YL+ M IG+LT E+VQ+L  ++D+L GEVD+L KATP SLW KDLDAL+ +LD QD  DA  EA+R       MK DG    ++APKNPRK  K   N E   +    ++ SA+ET +NV EV  PKGKAGPKKAPA+KGK+ S+LR  D++DDDE+L LKDRLAAYN+ +SSPD SE ME ++P+++ +K+  + K +    +  ++S D++ + E   ISDD D E+EV    K+ GRK  A NSK AAKP AAP   KKRG A   K SQLV QKLIT+VLKPA+ S +SPEKKVR+MR SPFNKKS SVL R++ ++                S   GS+E   +V    ARP+R  NR K  YV+SDS++
Sbjct:    7 AKLPLQSSNNANIVLPTGKTIEETYQKKSQLEHILLRPDTYIGSIEKHSQTLWVFENDAMVHRQISYVPGLYKIFDEILVNAADNKQRDPRMDSVKIVINVEENFISVYNNGDGVPVEVHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIESADGRRQKKYKQVFSNNMGNKSQPIISKCKESENWTKVTYKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRVPVKSFSDYCDLYLQSAAKTRPDPLPRIVEKVNERWEVCASLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHIIGIVNKKNKNANLKAHSVKNHLWVFVNALIDNPAFDSQTKETLTLRQSSFGSKCELSQEFLKKVA-KSGVVENLLSWADFKQSKDLKKTDGTKRQRITGITKLEDANDAGGKNSDRCTLILTEGDSAKALAMAGISVVGRNFYGVFPLRGKLLNVREASHKQIMDNAEIQYIKQILGLQHGKVYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATH----KNGRVLSFYTMPEYESWKESLSGNATGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFIWVDDNDGEAIELAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFINKELILFSLADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASAIIGMAQDFVGSNNINLLQPNGQFGTRNQGGKDHASARYVYTRLSPITRSLFPKDDDILLDYLNEDGQSIEPTWYMPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIIGNIRRLLNNEPMEPMEPWYKGFRGTIEKTATKEAGASYTVSGIVEEVDETTIRVTELPVRKWTQDYKEFLESIMMGNEKVKDPFIKEFRDHTDDTTVYLDIIMSEENLLMAKQEGLLKKFKLTTTISTSNMHLFDSQGIIKKFDNPEQILEEFFHLRLEFYEKRKKVLLDNLQLELLKLDNKVRFILAVVEGSIIVSNRKRADLFLELKEKGFTPFPKKKSVEAAVAGSIEDAEETEESSEVATSKG-VRASDYEYLISMAIGSLTLEKVQELCADRDKLKGEVDDLIKATPKSLWTKDLDALESQLDEQDISDAQAEAARKEMRSKAMKDDGPKPTRQAPKNPRKYNKKASNTEPTTEPMEISSSSALET-NNVVEVAKPKGKAGPKKAPARKGKTFSVLRDEDDEDDDEVLALKDRLAAYNLGSSSPDQSETMETEIPKREPSKRATTKKPLV---SVTEISDDDDDQIE---ISDDEDFELEVEAAPKEKGRKKTA-NSK-AAKPTAAP---KKRGQA--NKTSQLVGQKLITEVLKPADVSKISPEKKVRRMRPSPFNKKSGSVLERLSQQETDKISPESEEQEESPASNASGSTEESAQVVVPRARPRRGGNRGKAKYVMSDSEN 1472    

BLAST of DCAR_022381 vs. ExPASy Swiss-Prot and TrEMBL without DCAR
Match: A0A1U7YTY7 (DNA topoisomerase 2 {ECO:0000256|RuleBase:RU362094} (5.6.2.2 {ECO:0000256|RuleBase:RU362094}))

HSP 1 Score: 1989.93 bits (5154), Expect = 0.000e+0
Identity = 1009/1492 (67.63%), Postives = 1189/1492 (79.69%), Query Frame = 0
 

Query:    5 PLQTNNISN---------TAKSIEETYQKKTQLEHILLRPDTYIGSIEKHTSSLWVYEDSEMVSRSVSYVPGLYKIFDEILVNAADNKQRDPKMDTVKVVIDVDNTLISVYNNGDGVPVEIHKEEGVYVPELIFGHLLTSSNYDDDQKKTTGGRNGYGAKLANIFSTEFVIETADGKRLKKYKQVFSNNMGNKTEPHITKCKESDNWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAGCLGRSVKVELNGERVPIKSFTDYIDLYLKSANKDKEDPLPRFVERVNSRWEICVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNQLTSHIIASISKKNKKVNLKPHAVKNHLWVFVNALIDNPAFDSQTKETLTIRQNSFGSECKLSEDFLKKVVNKSGIVDSLLAWAEFKEKKDLKKTDG-KKGRVTGIPKLEDANKAGGSQSQKCTLILTEGDSAKSLAMAGLSVVGRDLYGVFPLRGKLLNVREASHKQIMENAEIQNIKKILGLQHGKAYEDVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPHFMIEFITPIVKATKNEGAKNEIVLSFYTIPEYENWKESLGDALRGWTIKYYKGLGTSDATEAKAYFRDLGTHKKDFIWAGDDDGDAIELAFSKKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFTKQAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDF--------------------GGKDHASARYIYTELAPITRYMFPKDDDILLDYLYEDGQKIEPYWYVPVVPMVLVNGSEGIGTGWSTYVPNYNPRDIAANIRRLLMGEPMQPMDPWYKGFRGTIEKSATKEAGAGYTVSGLIEEIDDTNVRITELPIRRWTQDYKEFLESSMIGNEKIK-AFIKNYSNQSDDCTVHFDVEMSEENMLIAKQEGLLKKFKLTANISTSNMHLFDPKGVIKKYDSPEQILEDFYHVRFDLYKKRQAR---------------------VVEGKIKVSNRKKADLFLELKEKGFTPFPKKTK-VEELVAGATDAVETEDNSQGSGGAGSAKLGDYDYLLKMEIGTLTAERVQKLLKEKDQLIGEVDELRKATPTSLWLKDLDALDRELDAQDQRDADGEASRVSTYENRMKPDG--SAKKAPKNPRKS-TKNVKNAETVVK-LTGTATDSAMETEDNVQEVVNPKGKAG-PKKAPAKKGKSTSILRDEDDDDEILDLKDRLAAYNINSSPDHSEVMEVDVPQKQATKKPPSGKSVAGKKAS--LDVSGDEE-------QEFEIEDISDDNDSEVEV---VKGKKGGRKPAAGNSKAAAKPPAAPAATKKRGPAATTKKSQLVNQKLITDVLKPAENSGVSPEKKVRKMRASPFNKKSSSVLGRVAAKDDSVS-LGSSLDTSGGGGS-------SETMTRVARPQRVNRTKTTYVL 1418
            PLQT+NI+N         + K+IEETYQKK+QLEHILLRPDTY+GSIEKHT +LWVY+  EMV R V+YVPGLYKIFDEILVNAADNKQRDP MD+VKVVID +   ISVYNNGDGVPVEIH+EEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKL NIFSTEF+IETADGKR KKYKQVFSNNMG K+EP ITKCK S+NWTKV+FKPDLAKFN+THLEDDVVALMKKRV+D+AGCLG++VKVELNG+RVP+KSF DY++LYL+SA+K + +PLPR  E+V+ RWE+CVS SEGQFQQVSFVNGIATIKGGTHVDYVTNQ+T+H++  ++KKNK  NLK H VKNHLWVFVN+LIDNPAFDSQTKETLT RQ+SFGS+C+LS++FLKKV  KSG+V++LL+WA+FK+ KDLKKTDG K+ R+TGI KLEDAN AGG  S+KCTLILTEGDSAK+LAMAG+SVVGR+ YGVFPLRGKLLNVREA+HKQIM+NAEIQNIK+ILGLQHGK Y+ VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+P F++EFITPIVKAT     KN  VLSFY++PEYE+WK  LG    GW+IKYYKGLGTS + E K YF+DL  HKKDF+W  D DGDAIELAFSKKKIEARKNWLRQFEPGT LDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFC+FKRN  K+AKVAQFSGYVSEHSAYHHGEQSL STI+GMAQD+                    GGKDHASARYIYT L+PITR++FPK DDILLDYL EDGQ IEP WY+P++P VLVNGSEGIGTGWS+Y+PNYNPRDI ANI+RLL GEPM+PMDPWYKGF+G IEK+ATKEAG+ YTVSG+IEEI++T +RITELPIRRWTQDYKEFLES M GN+KIK  FIK+Y   +DD TVHF++ +SEEN+++AKQEGL+KKFKLT  ISTSNMHLFDPKG IKKYD+PEQILE+F+H+R + Y+KR+                       VV+G+I VSNRK+ DLFLEL++KGFTPFPKKTK +E  VAGA +  E  + +     +   +  DY+YLL M IGTLT E+VQ+L  ++D+L  EV+ELRKATP SLW+ DLDAL++ELD QD+ DA  E +R       M   G  ++++APKNPRK+  K    +ETV + +  ++  SAMET   V EVV PKG+ G PKKAPAKK  +  ++  ++DD ++++LK+RLAAYN++SSP+ S VME +V +  A KK PS ++ A K+ S   ++S D++       +E  I +I  D D E EV    KG +GGRKPAA N KAA       A+TKKRG  A  K++ ++ QK ITD+LKPAEN+GVSPEKKVRKMRASPFNKKS SVLGRV      +S +GS    +G   +       SE +    RPQRVNR K  YV+
Sbjct:    8 PLQTSNIANVPSSRPLVGSGKTIEETYQKKSQLEHILLRPDTYVGSIEKHTQTLWVYDGGEMVHRPVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDAEQNCISVYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFIIETADGKRQKKYKQVFSNNMGKKSEPAITKCKGSENWTKVTFKPDLAKFNLTHLEDDVVALMKKRVIDLAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSASKSRPEPLPRITEKVSERWEVCVSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMTIVNKKNKNANLKAHTVKNHLWVFVNSLIDNPAFDSQTKETLTTRQSSFGSKCELSQEFLKKVA-KSGVVENLLSWADFKQSKDLKKTDGAKRQRITGITKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVVGRNNYGVFPLRGKLLNVREATHKQIMDNAEIQNIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATH----KNGKVLSFYSMPEYESWK-XLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDRDGDAIELAFSKKKIEARKNWLRQFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPWYKGFKGLIEKTATKEAGSSYTVSGIIEEINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKEPFIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKGTIKKYDNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRVDLFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELCSDRDKLNHEVEELRKATPNSLWMNDLDALEKELDEQDKNDAQAEEARKELKNRVMSEAGMKASRQAPKNPRKTNAKKPSTSETVTESVAASSVGSAMET---VPEVVKPKGRGGRPKKAPAKKQDNMRLVDSDEDDVDVIELKERLAAYNLDSSPEQSAVMETEVAKVPAKKKEPSKRAAAQKQPSSYTEISDDDDGMDVQTIREESIGEIVSDEDFEPEVEEAPKGGRGGRKPAA-NGKAA-------ASTKKRG--AANKQTSVLGQKKITDLLKPAENAGVSPEKKVRKMRASPFNKKSGSVLGRVGGMVGDISPMGSEEQQTGTSSASTDSAELSEVVPARPRPQRVNRGKAKYVI 1480    

BLAST of DCAR_022381 vs. ExPASy Swiss-Prot and TrEMBL without DCAR
Match: A0A6P6WGY5 (DNA topoisomerase 2 {ECO:0000256|RuleBase:RU362094} (5.6.2.2 {ECO:0000256|RuleBase:RU362094}))

HSP 1 Score: 1988.77 bits (5151), Expect = 0.000e+0
Identity = 1025/1485 (69.02%), Postives = 1199/1485 (80.74%), Query Frame = 0
 

Query:    2 ANRPLQTNNISN----TAKSIEETYQKKTQLEHILLRPDTYIGSIEKHTSSLWVYEDSEMVSRSVSYVPGLYKIFDEILVNAADNKQRDPKMDTVKVVIDVDNTLISVYNNGDGVPVEIHKEEGVYVPELIFGHLLTSSNYDDDQKKTTGGRNGYGAKLANIFSTEFVIETADGKRLKKYKQVFSNNMGNKTEPHITKCKESDNWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAGCLGRSVKVELNGERVPIKSFTDYIDLYLKSANKDKEDPLPRFVERVNSRWEICVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNQLTSHIIASISKKNKKVNLKPHAVKNHLWVFVNALIDNPAFDSQTKETLTIRQNSFGSECKLSEDFLKKVVNKSGIVDSLLAWAEFKEKKDLKKTDG-KKGRVTGIPKLEDANKAGGSQSQKCTLILTEGDSAKSLAMAGLSVVGRDLYGVFPLRGKLLNVREASHKQIMENAEIQNIKKILGLQHGKAYEDVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPHFMIEFITPIVKATKNEGAKNEIVLSFYTIPEYENWKESLGDALRGWTIKYYKGLGTSDATEAKAYFRDLGTHKKDFIWAGDDDGDAIELAFSKKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFTKQAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDF--------------------GGKDHASARYIYTELAPITRYMFPKDDDILLDYLYEDGQKIEPYWYVPVVPMVLVNGSEGIGTGWSTYVPNYNPRDIAANIRRLLMGEPMQPMDPWYKGFRGTIEKSATKEAGAGYTVSGLIEEIDDTNVRITELPIRRWTQDYKEFLESSMIGNEKIK-AFIKNYSNQSDDCTVHFDVEMSEENMLIAKQEGLLKKFKLTANISTSNMHLFDPKGVIKKYDSPEQILEDFYHVRFDLYKKRQ---------------------ARVVEGKIKVSNRKKADLFLELKEKGFTPFPKKTKVEELVAGAT-DAVETEDNSQGSGGAGSAKLGDYDYLLKMEIGTLTAERVQKLLKEKDQLIGEVDELRKATPTSLWLKDLDALDRELDAQDQRDADGEASRVSTYENRMKPDG--SAKKAPKNPRKSTKNVKNAETVVKLTGTATDSAMETEDNVQEVVNPKGKAGPKKAPAKKGKSTSILR--DEDDDDEILDLKDRLAAYNI-NSSPDHSEVMEVDVPQKQATKKPPSGKSVAGKKASLDVSGDEEQEFEIEDISDDNDSEVEV-VKGKKGGRKPAAGNSKAAAKPPAAPAATKKRGPAATTKKSQLVNQKLITDVLKPAENSGVSPEKKVRKMRASPFNKKSSSVLGRVAAKDDSV----SLGSSLDTSGGGGSSETMTRV----ARPQR-VNRTKTTYVLSDSDD 1423
            A  PLQ++N +N    T K+IEETYQKK+QLEHILLRPDTYIGSIEKH+ +LWV+E+  MV R +SYVPGLYKIFDEILVNAADNKQRDPKMD+VKVVI+V+   ISVYNNGDGVPVE+H+EEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKL NIFSTEFVIETADGKR KKYKQVFSNNMGNK++P I+KCKES+NWTKV+FKPDLAKFNMTHLEDDV+ALMKKRVVD+AGCLG++VKVELNG+RVP+KSF+DY DLYL+SA K + DPLPR VE+VN RWE+C S SEGQFQQVSFVNGIATIKGGTHVDYVTNQ+T+HII  ++KKNK  NLK H+VKNHLWVFVNALIDNPAFDSQTKETLT+RQ+SFGS+C+LS++FLKKV  KSG+V++LL+WA+FK+ KDLKKTDG K+ R+TGI KLEDAN AGG  S +CTLILTEGDSAK+LAMAG+SVVGR+ YGVFPLRGKLLNVREASHKQIM+NAEIQ IK+ILGLQHGK Y+ VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+P F++EFITPIVKAT     KN   LSFYT+PEYE+WKESL     GW+IKYYKGLGTS + E K YF+DLG HKKDFIW  D+DG+AIELAFSKKKIEARKNWLRQ+EPGT+LDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF K+ K+AQFSGYVSEHSAYHHGEQSLAS+I+GMAQDF                    GGKDHASARYIYT L+PITR +FPKDDD+LLDYL EDGQ IEP WY+P++PMVLVNGSEGIGTGWS+Y+PNYNPRDI ANIRRLL  EPM+PM+PWY+GFRGTIEK+ATKEAGA YTVSG++EE+D+T +R+TELPIR+WTQDYKEFLES M+GNEK+K  FIK + + +DD TV+ ++ MSEEN+L+AK EGLLKKFKLT  ISTSNMHLFD +G+IKK+D+PEQIL +F+H+R + Y+KR+                       VVEG I VSNRK+ADLFLELKEKGFTPFPKK  VE  VAG+  DA ETE++S+ +   G  +  DY+YLL M IG+LT E+VQ+L  ++D+L GEVD+LRKATP SLW KDLDAL+ +LD QD  DA  EA+R       MK DG    ++APKNPRK  +   N E   +    ++ SA+ET +NV EV  PKGKAGPKKAPA+KGK++S+LR  D++DDDE+L LKDRLAAYN+ +SSPD SE ME ++P+++ +K+  + K +       D  GD++Q   IE ISDD D E+EV    K+ GRK  A +  A        AA KKRG A   K SQLV QKLIT+VLKPA+ S +SPEKKVR+MR SPFNKKS SVL R++ +++      S G     S   GS+E   +V    ARPQR  NR K  YVLSDS++
Sbjct:    7 AKLPLQSSNNANIVLPTGKTIEETYQKKSQLEHILLRPDTYIGSIEKHSQTLWVFENDAMVHRQISYVPGLYKIFDEILVNAADNKQRDPKMDSVKVVINVEENFISVYNNGDGVPVEVHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSNNMGNKSQPIISKCKESENWTKVTFKPDLAKFNMTHLEDDVLALMKKRVVDLAGCLGKTVKVELNGQRVPVKSFSDYCDLYLQSAAKTRPDPLPRIVEKVNERWEVCASLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHIIGIVNKKNKNANLKAHSVKNHLWVFVNALIDNPAFDSQTKETLTLRQSSFGSKCELSQEFLKKVA-KSGVVENLLSWADFKQSKDLKKTDGAKRQRITGITKLEDANDAGGKNSDRCTLILTEGDSAKALAMAGISVVGRNFYGVFPLRGKLLNVREASHKQIMDNAEIQYIKQILGLQHGKVYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATH----KNGRALSFYTMPEYESWKESLSGNATGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFIWVDDNDGEAIELAFSKKKIEARKNWLRQYEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKELKIAQFSGYVSEHSAYHHGEQSLASSIIGMAQDFVGSNNINLLQPNGQFGTRNQGGKDHASARYIYTRLSPITRSLFPKDDDVLLDYLNEDGQSIEPTWYMPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANIRRLLNNEPMEPMEPWYRGFRGTIEKTATKEAGASYTVSGVVEEVDETTIRVTELPIRKWTQDYKEFLESIMMGNEKVKDPFIKEFRDHTDDTTVYLEIIMSEENLLMAKHEGLLKKFKLTTTISTSNMHLFDSQGIIKKFDNPEQILGEFFHLRLEFYEKRKKVLLDNLQLEHLKLDNKVRFILAVVEGSIIVSNRKRADLFLELKEKGFTPFPKKKSVEAAVAGSIEDAEETEESSEVATSKG-VRASDYEYLLSMAIGSLTLEKVQELCADRDKLKGEVDDLRKATPKSLWTKDLDALESQLDEQDISDAQAEAARKEMRRKAMKDDGPKPTRQAPKNPRKYNRKASNTEPTTEPMEISSSSALET-NNVVEVAKPKGKAGPKKAPARKGKTSSVLRDEDDEDDDEVLALKDRLAAYNLGSSSPDQSETMETEIPKREPSKRATTKKPLVSVTEISD--GDDDQ---IE-ISDDEDFELEVEAAPKEKGRKKTANSKAAKPA-----AAPKKRGQA--NKTSQLVGQKLITEVLKPADVSKISPEKKVRRMRPSPFNKKSGSVLERLSQQENDKISPESEGQESPASNASGSTEESAQVVVPRARPQRGGNRGKAKYVLSDSEN 1471    

BLAST of DCAR_022381 vs. ExPASy Swiss-Prot and TrEMBL without DCAR
Match: A0A1U7YMW7 (DNA topoisomerase 2 {ECO:0000256|RuleBase:RU362094} (5.6.2.2 {ECO:0000256|RuleBase:RU362094}))

HSP 1 Score: 1986.85 bits (5146), Expect = 0.000e+0
Identity = 1009/1492 (67.63%), Postives = 1189/1492 (79.69%), Query Frame = 0
 

Query:    5 PLQTNNISN---------TAKSIEETYQKKTQLEHILLRPDTYIGSIEKHTSSLWVYEDSEMVSRSVSYVPGLYKIFDEILVNAADNKQRDPKMDTVKVVIDVDNTLISVYNNGDGVPVEIHKEEGVYVPELIFGHLLTSSNYDDDQKKTTGGRNGYGAKLANIFSTEFVIETADGKRLKKYKQVFSNNMGNKTEPHITKCKESDNWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAGCLGRSVKVELNGERVPIKSFTDYIDLYLKSANKDKEDPLPRFVERVNSRWEICVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNQLTSHIIASISKKNKKVNLKPHAVKNHLWVFVNALIDNPAFDSQTKETLTIRQNSFGSECKLSEDFLKKVVNKSGIVDSLLAWAEFKEKKDLKKTDG-KKGRVTGIPKLEDANKAGGSQSQKCTLILTEGDSAKSLAMAGLSVVGRDLYGVFPLRGKLLNVREASHKQIMENAEIQNIKKILGLQHGKAYEDVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPHFMIEFITPIVKATKNEGAKNEIVLSFYTIPEYENWKESLGDALRGWTIKYYKGLGTSDATEAKAYFRDLGTHKKDFIWAGDDDGDAIELAFSKKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFTKQAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDF--------------------GGKDHASARYIYTELAPITRYMFPKDDDILLDYLYEDGQKIEPYWYVPVVPMVLVNGSEGIGTGWSTYVPNYNPRDIAANIRRLLMGEPMQPMDPWYKGFRGTIEKSATKEAGAGYTVSGLIEEIDDTNVRITELPIRRWTQDYKEFLESSMIGNEKIK-AFIKNYSNQSDDCTVHFDVEMSEENMLIAKQEGLLKKFKLTANISTSNMHLFDPKGVIKKYDSPEQILEDFYHVRFDLYKKRQAR---------------------VVEGKIKVSNRKKADLFLELKEKGFTPFPKKTK-VEELVAGATDAVETEDNSQGSGGAGSAKLGDYDYLLKMEIGTLTAERVQKLLKEKDQLIGEVDELRKATPTSLWLKDLDALDRELDAQDQRDADGEASRVSTYENRMKPDG--SAKKAPKNPRKS-TKNVKNAETVVK-LTGTATDSAMETEDNVQEVVNPKGKAG-PKKAPAKKGKSTSILRDEDDDDEILDLKDRLAAYNINSSPDHSEVMEVDVPQKQATKKPPSGKSVAGKKAS--LDVSGDEE-------QEFEIEDISDDNDSEVEV---VKGKKGGRKPAAGNSKAAAKPPAAPAATKKRGPAATTKKSQLVNQKLITDVLKPAENSGVSPEKKVRKMRASPFNKKSSSVLGRVAAKDDSVS-LGSSLDTSGGGGS-------SETMTRVARPQRVNRTKTTYVL 1418
            PLQT+NI+N         + K+IEETYQKK+QLEHILLRPDTY+GSIEKHT +LWVY+  EMV R V+YVPGLYKIFDEILVNAADNKQRDP MD+VKVVID +   ISVYNNGDGVPVEIH+EEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKL NIFSTEF+IETADGKR KKYKQVFSNNMG K+EP ITKCK S+NWTKV+FKPDLAKFN+THLEDDVVALMKKRV+D+AGCLG++VKVELNG+RVP+KSF DY++LYL+SA+K + +PLPR  E+V+ RWE+CVS SEGQFQQVSFVNGIATIKGGTHVDYVTNQ+T+H++  ++KKNK  NLK H VKNHLWVFVN+LIDNPAFDSQTKETLT RQ+SFGS+C+LS++FLKKV  KSG+V++LL+WA+FK+ KDLKKTDG K+ R+TGI KLEDAN AGG  S+KCTLILTEGDSAK+LAMAG+SVVGR+ YGVFPLRGKLLNVREA+HKQIM+NAEIQNIK+ILGLQHGK Y+ VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+P F++EFITPIVKAT     KN  VLSFY++PEYE+WK  LG    GW+IKYYKGLGTS + E K YF+DL  HKKDF+W  D DGDAIELAFSKKKIEARKNWLRQFEPGT LDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFC+FKRN  K+AKVAQFSGYVSEHSAYHHGEQSL STI+GMAQD+                    GGKDHASARYIYT L+PITR++FPK DDILLDYL EDGQ IEP WY+P++P VLVNGSEGIGTGWS+Y+PNYNPRDI ANI+RLL GEPM+PMDPWYKGF+G IEK+ATKEAG+ YTVSG+IEEI++T +RITELPIRRWTQDYKEFLES M GN+KIK  FIK+Y   +DD TVHF++ +SEEN+++AKQEGL+KKFKLT  ISTSNMHLFDPKG IKKYD+PEQILE+F+H+R + Y+KR+                       VV+G+I VSNRK+ DLFLEL++KGFTPFPKKTK +E  VAGA +  E  + +     +   +  DY+YLL M IGTLT E+VQ+L  ++D+L  EV+ELRKATP SLW+ DLDAL++ELD QD+ DA  E +R       M   G  ++++APKNPRK+  K    +ETV + +  ++  SAMET   V EVV PKG+ G PKKAPAKK  +  ++  ++DD ++++LK+RLAAYN++SSP+ S VME +V +  A KK PS ++ A K+ S   ++S D++       +E  I +I  D D E EV    KG +GGRKPAA N KAA       A+TKKRG  A  K++ ++ QK ITD+LKPAEN+GVSPEKKVRKMRASPFNKKS SVLGRV      +S +GS    +G   +       SE +    RPQRVNR K  YV+
Sbjct:    8 PLQTSNIANVPSSRPLVGSGKTIEETYQKKSQLEHILLRPDTYVGSIEKHTQTLWVYDGGEMVHRPVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDAEQNCISVYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFIIETADGKRQKKYKQVFSNNMGKKSEPAITKCKGSENWTKVTFKPDLAKFNLTHLEDDVVALMKKRVIDLAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSASKSRPEPLPRITEKVSERWEVCVSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMTIVNKKNKNANLKAHTVKNHLWVFVNSLIDNPAFDSQTKETLTTRQSSFGSKCELSQEFLKKVA-KSGVVENLLSWADFKQSKDLKKTDGAKRQRITGITKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVVGRNNYGVFPLRGKLLNVREATHKQIMDNAEIQNIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATH----KNGKVLSFYSMPEYESWK-XLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDRDGDAIELAFSKKKIEARKNWLRQFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPWYKGFKGLIEKTATKEAGSSYTVSGIIEEINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKEPFIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKGTIKKYDNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRVDLFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELCSDRDKLNHEVEELRKATPNSLWMNDLDALEKELDEQDKNDAQAEEARKELKNRVMSEAGMKASRQAPKNPRKTNAKKPSTSETVTESVAASSVGSAMET---VPEVVKPKGRGGRPKKAPAKK-DNMRLVDSDEDDVDVIELKERLAAYNLDSSPEQSAVMETEVAKVPAKKKEPSKRAAAQKQPSSYTEISDDDDGMDVQTIREESIGEIVSDEDFEPEVEEAPKGGRGGRKPAA-NGKAA-------ASTKKRG--AANKQTSVLGQKKITDLLKPAENAGVSPEKKVRKMRASPFNKKSGSVLGRVGGMVGDISPMGSEEQQTGTSSASTDSAELSEVVPARPRPQRVNRGKAKYVI 1479    

BLAST of DCAR_022381 vs. ExPASy Swiss-Prot and TrEMBL without DCAR
Match: A0A6P6VWH2 (DNA topoisomerase 2 {ECO:0000256|RuleBase:RU362094} (5.6.2.2 {ECO:0000256|RuleBase:RU362094}))

HSP 1 Score: 1981.84 bits (5133), Expect = 0.000e+0
Identity = 1017/1486 (68.44%), Postives = 1196/1486 (80.48%), Query Frame = 0
 

Query:    2 ANRPLQTNNISN----TAKSIEETYQKKTQLEHILLRPDTYIGSIEKHTSSLWVYEDSEMVSRSVSYVPGLYKIFDEILVNAADNKQRDPKMDTVKVVIDVDNTLISVYNNGDGVPVEIHKEEGVYVPELIFGHLLTSSNYDDDQKKTTGGRNGYGAKLANIFSTEFVIETADGKRLKKYKQVFSNNMGNKTEPHITKCKESDNWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAGCLGRSVKVELNGERVPIKSFTDYIDLYLKSANKDKEDPLPRFVERVNSRWEICVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNQLTSHIIASISKKNKKVNLKPHAVKNHLWVFVNALIDNPAFDSQTKETLTIRQNSFGSECKLSEDFLKKVVNKSGIVDSLLAWAEFKEKKDLKKTDG-KKGRVTGIPKLEDANKAGGSQSQKCTLILTEGDSAKSLAMAGLSVVGRDLYGVFPLRGKLLNVREASHKQIMENAEIQNIKKILGLQHGKAYEDVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPHFMIEFITPIVKATKNEGAKNEIVLSFYTIPEYENWKESLGDALRGWTIKYYKGLGTSDATEAKAYFRDLGTHKKDFIWAGDDDGDAIELAFSKKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFTKQAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDF--------------------GGKDHASARYIYTELAPITRYMFPKDDDILLDYLYEDGQKIEPYWYVPVVPMVLVNGSEGIGTGWSTYVPNYNPRDIAANIRRLLMGEPMQPMDPWYKGFRGTIEKSATKEAGAGYTVSGLIEEIDDTNVRITELPIRRWTQDYKEFLESSMIGNEKIK-AFIKNYSNQSDDCTVHFDVEMSEENMLIAKQEGLLKKFKLTANISTSNMHLFDPKGVIKKYDSPEQILEDFYHVRFDLYKKRQ---------------------ARVVEGKIKVSNRKKADLFLELKEKGFTPFPKKTKVEELVAGAT-DAVETEDNSQGSGGAGSAKLGDYDYLLKMEIGTLTAERVQKLLKEKDQLIGEVDELRKATPTSLWLKDLDALDRELDAQDQRDADGEASRVSTYENRMKPDG--SAKKAPKNPRKSTKNVKNAETVVKLTGTATDSAMETEDNVQEVVNPKGKAGPKKAPAKKGKSTSILR--DEDDDDEILDLKDRLAAYNI-NSSPDHSEVMEVDVPQKQATKKPPSGKSVAGKKASLDVSGDEEQEFEIEDISDDNDSEVEV-VKGKKGGRKPAAGNSKAAAKPPAAPAATKKRGPAATTKKSQLVNQKLITDVLKPAENSGVSPEKKVRKMRASPFNKKSSSVLGRVAAKD-----DSVSLGSSLDTSGGGGSSETMTRV----ARPQR-VNRTKTTYVLSDSDD 1423
            A  PLQ++N +N    T K+IEETYQKK+QLEHILLRPDTYIGSIEKH+ +LWV+E+  MV R +SYVPGLYKIFDEILVNAADNKQRDP+MD+VK+VI+V+   ISVYNNGDGVPVE+H+EEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKL NIFSTEFVIE+ADG+R KKYKQVFSNNMGNK++P I+KCKES+NWTKV++KPDLAKFNMTHLEDDVVALMKKRVVD+AGCLG++VKVELNG+RVP+KSF+DY DLYL+SA K + DPLPR VE+VN RWE+C S SEGQFQQVSFVNGIATIKGGTHVDYVTNQ+T+HII  ++KKNK  NLK H+VKNHLWVFVNALIDNPAFDSQTKETLT+RQ+SFGS+C+LS++FLKKV  KSG+V++LL+WA+FK+ KDLKKTDG K+ R+TGI KLEDAN AGG  S +CTLILTEGDSAK+LAMAG+SVVGR+ YGVFPLRGKLLNVREASHKQIM+NAEIQ IK+ILGLQHGK Y+ VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+P F++EFITPIVKAT     KN  VLSFYT+PEYE+WKESL     GW+IKYYKGLGTS + E K YF+DLG HKKDFIW  D+DG+AIELAFSKKKIEARKNWLRQFEPGT+LDQKEKLIKYSDF+NKELILFS+ADLQRSIPSMVDGLKPGQRKILFCSFKRNF K+AKVAQFSGYVSEHSAYHHGEQSLAS I+GMAQDF                    GGKDHASARY+YT L+PITR +FPKDDDILLDYL EDGQ IEP WY+P++PMVLVNGSEGIGTGWS+Y+PNYNPRDI  NIRRLL  EPM+PM+PWYKGFRGTIEK+ATKEAGA YTVSG++EE+D+T +R+TELP+R+WTQDYKEFLES M+GNEK+K  FIK + + +DD TV+ D+ MSEEN+L+AKQEGLLKKFKLT  ISTSNMHLFD +G+IKK+D+PEQILE+F+H+R + Y+KR+                       VVEG I VSNRK+ADLFLELKEKGFTPFPKK  VE  VAG+  DA ETE++S+ +   G  +  DY+YL+ M IG+LT E+VQ+L  ++D+L GEVD+L KATP SLW KDLDAL  +LD QD  DA  EA+R       MK DG    ++APKNPRK  K   N E   +    ++ SA+ET +NV EV  PKGKAGPKKAPA+KGK+ S+LR  D++DDDE+L LKDRLAAYN+ +SSPD SE ME ++P+++ +K+  + K +    +  ++S D++ + E   ISDD D E+EV    K+ GRK  A +  A        AA KKRG A   K SQLV QKLIT+VLKPA+ S +SPEKKVR+MR SPFNKKS SVL R++ ++                S   GS+E   +V    ARP+R  NR K  YV+SDS++
Sbjct:    7 AKLPLQSSNNANIVLPTGKTIEETYQKKSQLEHILLRPDTYIGSIEKHSQTLWVFENDAMVHRQISYVPGLYKIFDEILVNAADNKQRDPRMDSVKIVINVEENFISVYNNGDGVPVEVHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIESADGRRQKKYKQVFSNNMGNKSQPIISKCKESENWTKVTYKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRVPVKSFSDYCDLYLQSAAKTRPDPLPRIVEKVNERWEVCASLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHIIGIVNKKNKNANLKAHSVKNHLWVFVNALIDNPAFDSQTKETLTLRQSSFGSKCELSQEFLKKVA-KSGVVENLLSWADFKQSKDLKKTDGTKRQRITGITKLEDANDAGGKNSDRCTLILTEGDSAKALAMAGISVVGRNFYGVFPLRGKLLNVREASHKQIMDNAEIQYIKQILGLQHGKVYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATH----KNGRVLSFYTMPEYESWKESLSGNATGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFIWVDDNDGEAIELAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFINKELILFSLADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASAIIGMAQDFVGSNNINLLQPNGQFGTRNQGGKDHASARYVYTRLSPITRSLFPKDDDILLDYLNEDGQSIEPTWYMPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIIGNIRRLLNNEPMEPMEPWYKGFRGTIEKTATKEAGASYTVSGIVEEVDETTIRVTELPVRKWTQDYKEFLESIMMGNEKVKDPFIKEFRDHTDDTTVYLDIIMSEENLLMAKQEGLLKKFKLTTTISTSNMHLFDSQGIIKKFDNPEQILEEFFHLRLEFYEKRKKVLLDNLQLELLKLDNKVRFILAVVEGSIIVSNRKRADLFLELKEKGFTPFPKKKSVEAAVAGSIEDAEETEESSEVATSKG-VRASDYEYLISMAIGSLTLEKVQELCADRDKLKGEVDDLIKATPKSLWTKDLDALGSQLDEQDISDAQAEAARKEMRSKAMKDDGPKPTRQAPKNPRKYNKKASNTEPATEPMEISSSSALET-NNVVEVAKPKGKAGPKKAPARKGKTFSVLRDEDDEDDDEVLALKDRLAAYNLGSSSPDQSETMETEIPKREPSKRATTKKPLV---SVTEISDDDDDQIE---ISDDEDFELEVEAAPKEKGRKKTANSKAAKPA-----AAPKKRGQA--NKTSQLVGQKLITEVLKPADVSKISPEKKVRRMRPSPFNKKSGSVLERLSQQETDKISPESEEQEESPASNASGSTEESAQVVVPRARPRRGGNRGKAKYVMSDSEN 1472